Pigmented progressive purpuric dermatosis
https://en.wikipedia.org/wiki/Pigmented_purpuric_dermatosis
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Schamberg disease ― fireannach 26-bliadhna le bad de pigmentation asymptomatic agus telangiectasia air a’ chas.
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References
Pigmented Purpuric Dermatoses: A Complete Narrative Review 34070260 NIH
Tha Pigmented purpuric dermatoses (PPD) nam buidheann de shuidheachaidhean craiceann air an comharrachadh le raointean beaga de dh’ fhuil fon chraiceann mar thoradh air sèid capillary. Mar as trice bidh PPD a’ tòiseachadh mar spotan dearg gu purpaidh a thionndaidheas nas fhaide air adhart gu donn òir fhad ‘s a thèid an hemosiderin ath-ghlacadh.
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.
Schamberg Disease 32809367 NIH
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.
Characteristics and Clinical Manifestations of Pigmented Purpuric Dermatosis 26273156 NIH
Chaidh fiosrachadh mu euslaintich 113 le PPD a sgrùdadh, a’ toirt a-steach 38 a chaidh tro biopsy craiceann airson an sgrùdaidh seo. B’ e an seòrsa clionaigeach as cumanta galar Schamberg (60. 5%) . B’ e suidheachaidhean eile còmhla ri PPD mòr-fhulangas (15. 8%) , tinneas an t-siùcair (10. 5%) , agus feadhainn eile. Nochd eachdraidh cungaidh-leigheis statins (13. 2%) , luchd-bacadh beta (10. 5%) , agus feadhainn eile. Am measg nam factaran a dh’ fhaodadh a bhith co-cheangailte ri PPD bha galar analach àrd o chionn ghoirid (5. 3%) , seasamh fada a’ leantainn gu cuideam àrd orthostatic (2. 6%) , agus eacarsaich dian (2. 6%) . Chaidh làimhseachadh a thoirt do 36 euslaintich (94. 7%) - oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
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